Comprehensive Virology Vol 15: Virus-Host Interactions Immunity to Viruses

The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num­ bering, has probably reached that stage at which relatively few new-truly new-viruses will be...

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Bibliographic Details
Other Authors: Fraenkel-Conrat, Heinz (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1979, 1979
Edition:1st ed. 1979
Series:Comprehensive Virology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
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505 0 |a 1 Immune Responses, Immune Tolerance, and Viruses -- 1. Introduction -- 2. Immune System -- 3. Immune Responses in Nonviral Systems -- 4. Immune Responses in Viral Systems -- 5. Immune Tolerance in Viral Systems -- 6. Conclusion -- 7. References -- 2 Interaction of Viruses with Neutralizing Antibodies -- 1. Introduction -- 2. Methods -- 3. Antibody -- 4. Antigen-Antibody Interaction -- 5. Neutralization -- 6. Viral Neutralization -- 7. The Nonneutralized Fraction (NNF) -- 8. Neutralization by Antibody Fragments -- 9. Virolysis -- 10. Mechanisms -- 11. General Concluding Comments -- 12. References -- 3 Humoral Immunity to Viruses -- 1.Introduction -- 2. The Complement System -- 3. General Considerations of Virus Structure and Interactions with Humoral Elements -- 4. Nonimmune Non-Complement-Related Humoral Viral Neutralizing Factors -- 5. Antibody-Dependent Viral Neutralization -- 6. General Features of Antibody- and Complement-Dependent Viral Neutralization --  
505 0 |a Type II Interferon -- 8. Summary and Conclusions -- 9. References 
505 0 |a 7. Antibody- and Complement-Dependent Viral Neutralization: Nonlytic Mechanisms -- 8. Antibody- and Complement-Dependent Viral Neutralization: Lytic Mechanisms -- 9. Nonimmune Complement-Dependent Viral Inactivation -- 10. Conclusions -- 11. References -- 4 Cellular Immune Response to Viruses and the Biological Role of Polymorphic Major Transplantation Antigens -- 1. Introduction -- 2. Cellular Immunity and the Major Histocompatibility Gene Complex -- 3. Antigens Involved in Immune Recognition: Viral Antigens and Self Antigens Coded by the Major Histocompatibility Gene Complex -- 4. MHC Restriction and Immune Responsiveness -- 5. Polymorphism of MHC Products and MHC-Linked Susceptibility to Disease -- 6. References -- 5 Interferons -- 1. Introduction -- 2. Interferon Synthesis -- 3. Mechanisms of the Antiviral Activity -- 4. Molecular Characterization of Interferons -- 5. Interaction with the Immune System -- 6. Antitumor and Cell Multiplication Inhibitory Effects --  
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520 |a The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num­ bering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, bio­ chemical cytology, and high resolution microscopy and spec­ troscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua­ ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts