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140122 ||| eng |
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|a 9781461256281
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100 |
1 |
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|a Damjanov, Ivan
|e [editor]
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245 |
0 |
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|a The Human Teratomas
|h Elektronische Ressource
|b Experimental and Clinical Biology
|c edited by Ivan Damjanov, Barbara B. Knowles, Davor Solter
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250 |
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|a 1st ed. 1983
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260 |
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|a Totowa, NJ
|b Humana
|c 1983, 1983
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300 |
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|a XVI, 358 p
|b online resource
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505 |
0 |
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|a Alphafetoprotein (AFP) -- Other Yolk Sac Products -- Fibronectin -- Carcinoembryonic Antigen (CEA) -- Epithelial Membrane Antigen (EMA) -- Ferritin -- Lactate Dehydrogenase -- Tumors Devoid of Distinct Markers -- Radioimmunolocalization -- Multiple Markers -- Classification of Testicular Tumors -- References -- 9 Endocrine Aspects of Germ Cell Tumors -- Mechanisms Underlying Endocrine Manifestations -- Associated Clinical Syndromes -- Syndromes Associated with HCG Production -- Syndromes Arising from Steroid Hormone Production in the Absence of HCG -- Syndromes Resembling Those of Thyroid Hyperfunction -- Carcinoid Syndrome -- Syndromes of Ectopic Hormone Secretion -- References -- 10 Polypeptide Hormone-Producing Cells in Human Teratomas -- Testicular Teratomas -- Ovarian Teratomas -- Related Ovarian Neoplasms -- Ovarian Carcinoids -- Cystic Mucinous Tumors -- Biological Implications and Clinical Significance of Polypeptide Hormone-Producing Cells in Teratomas -- References --
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505 |
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|a 14 Human—Mouse Teratocarcinoma Hybrids: A Tool for Analysis of Gene Activity in Early Human Development -- Production of Microcell and Conventional Hybrids -- Induction of Differentiation in Human—Mouse Teratocarcinoma Hybrids -- Reexpression of Human Malic Enzyme by MCP-6 and the PCG Hybrids -- The Expression of HLA-A,B,C in Human EC Cell Lines and MCP-6 -- Analysis of X-Inactivation Using Somatic Cell Genetics -- Isolation of Developmentally Regulated Human DNA Sequences -- Summary and Conclusions -- References -- 15 Experimental Mouse Teratocarcinoma: A Model for Human Teratocarcinoma? -- Origin of Mouse Teratocarcinoma -- Nature of Teratocarcinoma Stem Cells -- Regulation of Teratocarcinogenesis -- Comparison of Mouse and Human ECC -- Concluding Remarks -- References
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505 |
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|a Associated Lesions and Abnormalities -- Twinning -- Association of Teratomas and Malformations -- Chromosomal Abnormalities and Genetic Predisposition to Teratomas -- Disturbances in the Immune System -- References -- 3 The Origin of Teratomas -- Dermoid Cyst (Benign Cystic Teratoma) of the Ovary -- Genetic Evidence in Favor of a Postmeiotic (Parthenogenic) Origin of Dermoid Cysts -- Teratomas of Testis -- The Application of Genetic Techniques to Germ Cell Tumors of the Testis -- Germ Cell Tumors of the Pineal Gland (and Its Environs) -- Teratomas of the Mediastinum -- The Origin of Teratomas of the Pineal Gland, Mediastinum, and Sacrococcygeal Region in the Neonatal Period and in Infancy -- Genetic and Chromosomal Observations on Extragonadal Teratomas and on Individuals Who Have Extragonadal Teratomas -- Teratomas Associated with Sex Chromosome Abnormalities -- X Chromosome Differentiation, Barr Body Formation, and Teratomas -- Discussion -- References --
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|a Patterns of Metastasis -- History of Metastases -- Effect of Chemotherapy on Metastasis -- Experimental Data -- Metastasis of Germ Cell Tumors of the Ovary -- Metastasis of Extragonadal Germ Cell Tumors -- Conclusions -- References -- 7 Neural Tissues in Human Teratomas -- Frequency of Nervous Tissue in Teratomas -- Types of Neuroectodermal Tissues Present in Teratomas -- Embryonal and Fetal Structures and Tissues -- Mature Structures and Tissues -- Reactive Phenomena in Teratoid Nervous Tissue -- Implants and Neurogenic Metastases in Teratomas -- Ultrastructural Findings in Teratoid Neuroectodermal Tissues -- Clinicopathological Significance of the Neural Components of Teratomas -- References -- 8 Biological Markers of Human Teratomas and Related Germ Cell Tumors -- Pathology -- Malignant Teratomas -- Seminoma -- Immunocytochemical Approach -- Localization of Placental Proteins -- Human Chorionic Gonadotropin (HCG) -- Other Placental Proteins -- Markers of Yolk Sac Differentiation --
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505 |
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|a 4 The Epidemiology of Human Teratomas -- Frequency -- Teratomas of the Ovary -- Testicular Teratomas -- Sacrococcygeal and Presacral Teratomas -- Mediastinal Teratomas -- Retroperitoneal Teratomas -- Renal Teratomas -- Intracranial Teratomas -- Intraspinal Teratomas -- Thyroid and Cervical Teratomas -- Nasopharyngeal Teratomas -- Cardiac, Gastric, Orbital, Hepatic, and Uterine Teratomas -- Conclusions -- References -- 5 Malignant Alteration in Benign Teratomas -- Ovary -- Squamous Cell Carcinoma -- Age and Incidence -- Symptoms -- Gross Pathology -- Histology -- Spread -- Diagnosis and Treatment -- Prognosis -- Carcinoid -- Adenocarcinoma -- Malignant Melanoma -- Sarcoma -- Miscellaneous Tumors -- Etiology and Pathogenesis of Malignant Alteration -- Malignant Alteration in Extraovarian Teratomas -- References -- 6 The Metastasis of Human Teratomas -- Metastasis of Germ Cell Tumors of the Testis -- Incidence and Natural History of Metastasis -- Experimental Data --
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505 |
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|a 11 Chemotherapy of Teratomas -- VAB-6 Combination Chemotherapy in Disseminated Cancer of the Testis -- Primary Mediastinal Germ Cell Tumors -- Germ Cell Tumors of the Ovary -- Adjuvant VAB-6 Chemotherapy Regimen in Resected Stage II-B Testis Cancer -- Concluding Remarks -- References -- 12 Human Testicular Germ Cell Tumors In Vitro -- Cell Lines from Human Testicular Germ Cell Tumors -- Some Characteristics of the Cell Lines -- Embryonal Carcinoma Lines -- Other Cell Lines from Testicular Germ Cell Tumors -- Production of Tumors in Athymic Mice -- Cytogenetics -- Virus Production by Human EC Cells -- Conclusion -- References -- 13 The Characteristics of Cell Lines Derived from Human Germ Cell Tumors -- Human Teratoma Xenograft Lines -- Human Teratocarcinoma Cell Lines Established In Vitro -- Biochemical Properties -- Major Histocompatibility Antigens -- Embryonic Antigens -- SSEA-3 -- Alkaline Phosphatase (ALP) -- Conclusion -- References --
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|a 1 History of Teratomas -- Early Morphologic and Clinical Studies of Ovarian Teratomas -- Theories of the Origin of Teratomas -- Early Morphologic and Clinical Studies of Testicular Teratomas -- Extragonadal Teratomas -- Teratomas in Animals -- Experimental Studies -- References -- 2 The Pathology of Human Teratomas -- Classification of Germ Cell Tumors -- Origin of Teratomas -- Testicular Teratomas -- Ovarian Teratomas -- Extragonadal Teratomas -- Histopathology -- Embryonal Carcinoma -- Somatic Tissues -- Extraembryonic Tissues -- Nonneoplastic Components of Teratomas -- Variant Forms of Teratomas and Related Lesions -- Monophyletic or Unilaterally Differentiated Teratomas -- Mixed Teratoid Tumors -- Mixed Mullerian Tumors -- Fetus in Fetu -- Site of Origin of Teratomas -- Ovarian Teratomas -- Testicular Teratomas -- Sacrococcygeal Teratomas -- Retroperitoneal Teratomas -- Mediastinal Teratomas -- Teratomas of the Neck -- Intracranial Teratomas -- Teratomas in Unusual Locations --
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653 |
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|a Pathology
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700 |
1 |
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|a Knowles, Barbara B.
|e [editor]
|
700 |
1 |
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|a Solter, Davor
|e [editor]
|
041 |
0 |
7 |
|a eng
|2 ISO 639-2
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989 |
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|b SBA
|a Springer Book Archives -2004
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490 |
0 |
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|a Contemporary Biomedicine
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028 |
5 |
0 |
|a 10.1007/978-1-4612-5628-1
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856 |
4 |
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|u https://doi.org/10.1007/978-1-4612-5628-1?nosfx=y
|x Verlag
|3 Volltext
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082 |
0 |
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|a 616.07
|