The Serotonin Receptors

Serotonin (5-HT) was isolated and chemically characterized nearly four decades ago, and is now generally accepted to function as a neurotransmitter and neuromodulatory agent. Early research focused on the measurement of concentrations, synthesis, and metabolism of 5-HT, and only recently has the foc...

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Bibliographic Details
Main Author: Sanders-Bush, Elaine
Format: eBook
Language:English
Published: Totowa, NJ Humana 1988, 1988
Edition:1st ed. 1988
Series:The Receptors
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Section 1: Historical Perspective
  • 1 Historical Perspectives
  • Section 2: Characterization of Serotonin Receptor Binding Sites
  • 2 Biochemistry and Pharmacology of the 5-HT1 Serotonin Binding Sites
  • 3 Pharmacology and Biochemistry of the 5-HT2 Receptor
  • 4 Autoradiographic Studies of Serotonin Receptors
  • Section 3: Biochemical Mechanisms of Receptor Action
  • 5 5-HT Receptors Coupled to Adenylate Cyclase
  • 6 5-HT Receptors Coupled to Phosphoinositide Hydrolysis
  • Section 4: Correlation of Binding Sites with Function
  • 7 Autoreceptors Regulating Serotonin Release
  • 8 Electrophysiology of Central Serotonin Receptor Subtypes
  • 9 Behavioral Models of Serotonin Receptor Activation
  • 10 Serotonin Receptors in Vascular Smooth Muscle
  • Section 5: Regulation of Serotonin Receptors
  • 11 Regulation of Serotonin Receptors and Responsiveness in the Brain
  • Section 6: Future Vistas
  • 12 Future Vistas