Introduction to Cellular Signal Transduction

Our understanding of biological communication has grown significantly during the past decade. The advances in knowledge about the chemical nature of signals and their corresponding reception by specialized cells have led to identification, characterization, purification, cloning, and expression of s...

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Bibliographic Details
Other Authors: Sitaramayya, Ari (Editor)
Format: eBook
Language:English
Published: Boston, MA Birkhäuser 1999, 1999
Edition:1st ed. 1999
Series:Hormones in Health and Disease
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • I: Overview
  • Overview
  • II: Receptors and G-proteins
  • 1. Cell Surface Receptors: Mechanisms of Signaling and Inactivation
  • 2. Heterotrimeric G-proteins: Structure, Regulation, and Signaling Mechanisms
  • 3. Ras- and Rho-Related Small Molecular Weight G-proteins: Structure and Signaling Mechanisms
  • III: Second Messengers
  • 4. Cyclic Nucleotides: Synthesis by Adenylyl and Guanylyl Cyclases
  • 5. Phospholipases: Generation of Lipid-Derived Second Messengers
  • 6. Cyclic Nucleotide Phosphodiesterases: Structural and Functional Aspects
  • IV: Novel Messengers
  • 7. Nitric Oxide: Synthesis and Intracellular Actions
  • V: Regulatory Mechanisms and Ion Transport in Signal Transduction
  • 8. Ionic Channels Mediating Sensory Transduction
  • 9. Bits for an Organic Microprocessor: Protein Phosphorylation/Dephosphorylation
  • VI: Applications of Signal Transduction in Disease and Drug Abuse
  • 10. Defects in Signal Transduction Proteins Leading to Disease
  • 11. Intracellular Messengers in Drug Addiction
  • Keyword Index