Advances in Male Mediated Developmental Toxicity

Bibliographic Details
Other Authors: Robaire, Bernard (Editor), Hales, Barbara F. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 2003, 2003
Edition:1st ed. 2003
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Gender-Specificity of Gamete Susceptibilities to Exposures
  • 1. Female-Specific Reproductive Toxicities Following Preconception Exposure to Xenobiotics
  • 2. Overview of Male Mediated Developmental Toxicity
  • Exposures and Effects: Occupational and Environmental
  • 3. Epidemiologic Evidence on Biological and Environmental Male Factors in Embryonic Loss
  • 4. Mechanisms of Male Mediated Developmental Toxicity Induced by Lead
  • 5. Paternal Exposure to Known Mutagens and Health of the Offspring:
  • 6. FISH (Fluorescence In Situ Hybridization) to Detect Effects of Smoking, Caffeine, and Alcohol on Human Sperm Chromosomes
  • Markers of Sperm Damage and Germ Line Genotoxicity
  • 7. Sperm Nuclear DNA Damage in the Human
  • 8. The Human Spermatozoon—Not Waving but Drowning
  • 9. Model Systems for Studying Germ Cell Mutagens: From Flies to Mammals
  • 10. Germline Mutation Induction at Mouse and Human Tandem Repeat DNA Loci
  • 11. PAINT/DAPI Analysis of Mouse Zygotes to Detect Paternally Transmitted Chromosomal Aberrations
  • Exposures and Effects: Causes of Cancer and Consequences of Treatment
  • 12. Paternal Occupation and Childhood Cancer
  • 13. Radiation and Malformations in a Murine Model
  • 14. Mechanisms of Action of Cyclophosphamide as a Male-Mediated Developmental Toxicant
  • 15. Chromosome Abnormalities in Human Sperm
  • Pregnancy Outcome
  • 16. Distinguishing between Fertilization Failure and Early Pregnancy Loss when Identifying Male-Mediated Adverse Pregnancy Outcomes
  • 17. ICSI, Male Pronuclear Remodeling and Cell Cycle Checkpoints
  • 18. Increased Incidence of Malformations in the Offspring of Male Mice Prenatally Exposed to Synthetic Estrogens
  • Strategies for Prevention
  • 19. Implications of Research in Male-Mediated Developmental Toxicity to Clinical Counsellors, Regulators,and Occupational Safety Officers
  • 20. Restoration of Spermatogenesis after Exposure to Toxicants: Genetic Implications
  • Future Directions
  • 21. Epigenetics: Role of Germ Cell Imprinting
  • 22. Efficiency and Safety of Animal Cloning
  • Workshop Reports
  • 23. Integrating New Tests of Sperm Genetic Integrity into Semen Analysis: Breakout Group Discussion
  • 24. Risk Assessment
  • 25. Study Designs for the Assessment of Male Mediated Developmental Toxicity
  • 26. Translational Research in Male Mediated Developmental Toxicity
  • 285
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