The Complement System Novel Roles in Health and Disease

As a phylogenetically old system complement is now regarded as a part of innate immunity. But it is much more than that. It bridges innate and adapted immunity, participates not only in host defense but also in many essential physiological processes, old and new diseases and adverse conditions. Inde...

Full description

Bibliographic Details
Other Authors: Szebeni, Janos (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 2004, 2004
Edition:1st ed. 2004
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • The Development of the “One-Hit” or “Single Site” Theory of Complement Mediated Immune Hemolysis
  • The Initiation Complexes of the Classical and Lectin Pathways
  • Complement Genetics
  • Regulation of Complement Receptor Gene Expression
  • Coordination of Adaptive Immune Responses by C3
  • Terminal Complement Complex: Regulation of Formation and Pathophysiological Functions
  • The Many Faces of the Membrane Regulators of Complement
  • New Insights into the Regulation of Complement Activation by Decay Accelerating Factor
  • The Role of Complement in Pregnancy and Fetal Loss
  • Complement Deficiencies: a 2004 Update
  • Microbial Evasion Mechanisms Against Human Complement
  • Complement-Mediated Antibody-Dependent Enhancement of Viral Infections
  • Tumor Cell Resistance to Complement-Mediated Lysis
  • Complement and Autoimmunity
  • The Complex Roles of Anaphylatoxins in Allergic Asthma and Autoimmune Diseases
  • Role of Complement in Allergy
  • Complement Activation-Related Pseudoallergy
  • The Role of Complement in Transplantation
  • Role of Complement in Myocardial Ischemia and Infarction
  • Role of Complement in Intestinal Ischemia/Reperfusion Induced Injury
  • Role of C5a and C5a Receptor in Sepsis
  • Role of Complement in Multi-Organ Dysfunction Syndrome
  • Therapeutic Manipulation of the Complement System
  • Activation and Inhibition of Complement by Immunoglobulins
  • Engineering Control of Complement Inhibition at the Cell Surface