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140122 ||| eng |
| 020 |
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|a 9780306468384
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| 100 |
1 |
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|a Della Corte, Laura
|e [editor]
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| 245 |
0 |
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|a Taurine 4
|h Elektronische Ressource
|b Taurine and Excitable Tissues
|c edited by Laura Della Corte, Ryan J. Huxtable, Giampietro Sgaragli, Keith F. Tipton
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| 250 |
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|a 1st ed. 2002
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| 260 |
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|a New York, NY
|b Springer US
|c 2002, 2002
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| 300 |
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|a XXIV, 652 p
|b online resource
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| 505 |
0 |
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|a Keynote Presentation -- Appreciations -- Plenary Presentations -- Basic Aspects and Peripheral Actions of Taurine -- Metabolic and Nutritional Aspects -- Taurine in the CNS -- Taurine Analogues and Metals: Health Care Aspects -- Taurine and Vision -- Taurine and Cell Homeostatic Mechanisms -- Clinical Aspects
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| 653 |
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|a Neurology
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| 653 |
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|a Neurology
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| 653 |
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|a Nutrition
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| 653 |
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|a Nutrition
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| 653 |
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|a Biochemistry
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| 653 |
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|a Pharmacology
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| 700 |
1 |
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|a Huxtable, Ryan J.
|e [editor]
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| 700 |
1 |
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|a Sgaragli, Giampietro
|e [editor]
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| 700 |
1 |
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|a Tipton, Keith F.
|e [editor]
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b SBA
|a Springer Book Archives -2004
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| 490 |
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|a Advances in Experimental Medicine and Biology
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| 028 |
5 |
0 |
|a 10.1007/b112581
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| 856 |
4 |
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|u https://doi.org/10.1007/b112581?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 572
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| 520 |
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|a Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3µM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from
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