Peptide Nucleic Acids Methods and Protocols

Exemplifying and illustrating recent exciting advances in PNA chemistry, the second edition of Peptide Nucleic Acids: Methods and Protocols serves as a vital complement to the first edition of the book. Since the discovery of peptide nucleic acids, many interesting new derivatives and analogues in t...

Full description

Bibliographic Details
Other Authors: Nielsen, Peter E. (Editor), Appella, Daniel H. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2014, 2014
Edition:1st ed. 2014
Series:Methods in Molecular Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • MiniPEG-gPNA
  • Cyclopentane Peptide Nucleic Acids
  • Chiral PNAs with Constrained Open-chain Backbones
  • Synthesis, Characterization and Evaluation of Radiometal-Containing Peptide Nucleic Acids
  • Preparation of Metal-Containing Peptide Nucleic Acid Bioconjugates on the Solid Phase
  • Formation and Characterization of PNA-Containing Heteroquadruplexes
  • Sequence Selective Recognition of Double Stranded RNA using Triple Helix-forming Peptide Nucleic Acids
  • Assembly of PNA-tagged Small Molecules, Peptides and Carbohydrates onto DNA Templates: Programming the  Combinatorial Pairing and Inter-ligand Distance
  • Site-selective Scission of Human Genome using PNA-based Artificial Restriction DNA Cutter
  • PNA Openers and their Applications for Bacterial DNA Diagnostics
  • DNA-templated Native Chemical Ligation of Functionalized Peptide Nucleic Acids – A Versatile Tool for Single Base Specific Detection of Nucleic Acids
  • Use of Peptide Nucleic Acids (PNAs) for Genotyping by Solution and Surface Methods
  • Analysis of PNA Hybridization by Surface Plasmon Resonance
  • PNA Fluorescent in situ Hybridization (FISH) For Rapid Microbiology and Cytogenetic Analysis
  • Rapid miRNA Imaging in Cells using Fluorogenic Templated Staudinger Reaction Between PNA-based Probes
  • Cellular Delivery of Peptide Nucleic Acids (PNAs)
  • Peptide Nucleic Acid Mediated Recombination For Targeted Genomic Repair and Modification
  • Antisense Effects of PNAs in Bacteria