Design, Analysis, and Interpretation of Genome-Wide Association Scans
This book presents the statistical aspects of designing, analyzing and interpreting the results of genome-wide association scans (GWAS studies) for genetic causes of disease using unrelated subjects. Particular detail is given to the practical aspects of employing the bioinformatics and data handlin...
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2014, 2014
|
| Edition: | 1st ed. 2014 |
| Series: | Statistics for Biology and Health
|
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Introduction to Genome-Wide Association Studies
- Topics of Quantitative Genetics
- An Introduction to Association Studies
- Correcting for Hidden Population Structure in Single Marker Association Testing and Estimation
- Haplotype Imputation for Association Analysis
- SNP Imputation for Association Studies
- Design of Large-scale Genetic Association Studies, Sample Size and Power
- Post-GWAS Analyses