Peptide Synthesis and Applications

Peptides are used ubiquitously for studies in biology, biochemistry, chemical biology, peptide based medicinal chemistry, and many other areas of research. There is a number of marketed peptide drugs, and the prospects for the development of new peptide drugs are very encouraging.  The second editio...

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Bibliographic Details
Other Authors: Jensen, Knud J. (Editor), Tofteng Shelton, Pernille (Editor), Pedersen, Søren L. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2013, 2013
Edition:2nd ed. 2013
Series:Methods in Molecular Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Solid-Phase Peptide Synthesis: An Introduction
  • Linkers, Resins and General Procedures for Solid-phase Peptide Synthesis
  • Peptide Release, Side-chain Deprotection, Work-up, and Isolation
  • Synthesis of Peptides using Tert-butyloxycarbonyl (Boc) as the α-amino Protection Group
  • Sequential Formation of Regioselective Disulfide Bonds in Synthetic Peptides with Multiple Disulfide Bonds
  • Synthesis of Cyclic Disulfide-Rich Peptides
  • Preparation of C-terminally Modified Chemokines by Expressed Protein Ligation
  • Synthesis of C-terminal Peptide Thioesters using Fmoc Based Solid-phase Peptide Chemistry
  • Backbone Amide Linker Strategy –Protocols for the Synthesis of C‑terminal Peptide Aldehydes
  • Synthesis of N-methylated Peptides: On-resin Methylation and Microwave-Assisted Couplings
  • Synthesis of Antimicrobial Peptoids
  • Synthesis of Lipidated Peptides
  • Solid-Phase Synthesis of Phosphopeptides
  • Synthesis of O-Glycopeptides and Construction of Glycopeptide Microarrays
  • Instruments for Automated Peptide Synthesis
  • Microwave-Assisted Solid-Phase Peptide Synthesis using the Biotage Syro Wave™
  • Microwave-Assisted Solid-Phase Peptide Synthesis Based on the Fmoc Protecting Group Strategy (CEM)