Systems Analysis of Chromatin-Related Protein Complexes in Cancer
Epigenetic modifications underlie all aspects of human physiology, including stem cell renewal, formation of cell types and tissues. They also underlie environmental impacts on human health, including aging and diseases like cancer. Consequently, cracking the epigenetic "code" is consider...
| Other Authors: | , , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2014, 2014
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| Edition: | 1st ed. 2014 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Preface
- Systematic proteomic analysis of histone demethylating enzymes linked to cancer
- Histone methylating protein complexes in cancer
- Chromatin protein-protein interaction networks linked to cancer
- Structural genomics and drug discovery for chromatin-related protein complexes involved in histone tail recognition
- Transcription factories and global chromatin (enhancer) interactions in cancer
- Long ncRNAs associated with chromatin complexes and their role in cancer
- Familial and somatic mutations of histone modifying enzymes in cancer
- Chromatin regulators arising from RNAi screens of transformed cancer cell lines
- Chromatin complexes in cancer
- Exploring dynamics of chromatin complexes in cancer based on quantitative proteomics
- Regulatory ncRNAs and their targets
- ncRNA regulatory networks in cancer
- Decoding BAF remodelling complexes in cancer
- Mediator/cohesin complex in cancer
- miRNAs targeting chromatin-related protein complexes regulate epigenetic states in cancer
- Polycomb group protein complexes in cancer stem cells
- Genetic interactions between chromatin factors in cancer cell lines
- Chromatin complexes in DNA repair
- Chromatin complexes in chromosome segregation
- Evolution, co-expression and domain architecture of CM complexes linked to cancer
- Index