Stem Cells and Cancer Stem Cells, Volume 5 : Therapeutic Applications in Disease and Injury

The fifth volume in the essential series on stem cell biology provides a detailed explanation of the mechanisms of self-renewing cancer stem cells, as well as their ability to generate the heterogeneous lineages of cancer cells that comprise tumors. It explores the unique resistance of cancer stem c...

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Corporate Author: SpringerLink (Online service)
Other Authors: Hayat, M.A. (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 2012, 2012
Edition:1st ed. 2012
Series:Stem Cells and Cancer Stem Cells
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Summary:The fifth volume in the essential series on stem cell biology provides a detailed explanation of the mechanisms of self-renewing cancer stem cells, as well as their ability to generate the heterogeneous lineages of cancer cells that comprise tumors. It explores the unique resistance of cancer stem cells to conventional chemotherapy techniques able to kill a tumor’s constituent cells. The contents also include a discussion of the myriad applications of a selection of stem cells in treating disease and tissue injury. The cells singled out include human mesenchymal, arterial, neural, cardiac, dental, limbal, and hematopoietic stem cells. The therapeutic utility of uniquely adaptable human embryonic stem cells, able to generate any human cell type, is explored in depth. The volume looks at their uses in tissue engineering and regenerative medicine, as well as pharmacological, toxicological, and cell differentiation research. It also sheds light on the processes by which embryonic stem cells begin to differentiate by aggregating into more complex embryoid bodies. With additional material on targeting self-renewal pathways in cancer stem cells, the use of mesenchymal stem cells in treating ischemic brain injury, and the phenomenon of neural stem cell proliferation around traumatic brain injuries, this richly diverse and hugely informative book is a powerful tool for deepening professional expertise among researchers and practitioners in this field
Physical Description:XIX, 309 p. 48 illus., 39 illus. in color online resource
ISBN:9789400729001