The Challenge of Highly Pathogenic Microorganisms Mechanisms of Virulence and Novel Medical Countermeasures

This book addresses the unique features of four microorganisms that constitute the top bioterror threat agents: Bacillus anthracis; Yersinia pestis, Francisella tularensis and Orthopoxviruses. Side-by-side updated information about their pathogenisis, virulence and epidemiology is provided in a sing...

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Bibliographic Details
Other Authors: Shafferman, Avigdor (Editor), Velan, Baruch (Editor), Ordentlich, Arie (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 2010, 2010
Edition:1st ed. 2010
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • The Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics
  • Proteomic Studies of Bacillus anthracis Reveal In Vitro CO2-Modulation and Expression During Infection of Extracellular Proteases
  • Dynamics of Bacillus anthracis Infection and Control Mechanisms
  • Survival and Trafficking of Yersinia pestis in Non-acidified Phagosomes in Murine Macrophages
  • The Inverse Relationship Between Cytotoxicity of Y. pestis and Its Virulence
  • The NlpD Lipoprotein of Yersinia pestis is Essential for Cell Separation and Virulence
  • Dissection of the Functions of the IglC Protein of Francisella tularensis
  • Yersinia pestis Lipopolysaccharide in Host-Pathogen Interactions
  • The Interactions Between Pathogens and Dendritic Cells: From Paralysis of Cells to Their Recruitment for Bacterial Colonization
  • Comparative Approaches to Identify Host Factors Specifically Targeted by Yersinia pestis During the Infectious Process
  • Poxvirus Entry into Host Cells
  • Effect of Disruption of mglA on the Virulence and Immunogenicity of the Francisella tularensis Live Vaccine Strain (LVS)
  • Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates
  • Modified Vaccinia Virus Ankara (MVA) based Vaccines – Immunostimulatory and Protective Capacity
  • Therapeutic Potential of Vaccinia Hyper Immune Sera in Mouse Models of Lethal Orthopoxviruses Infection
  • A Live Plaque Vaccine Candidate with Improved Safety and Immunogenecity
  • Protection Against Plague Afforded by Treatment with Polyclonal ?LcrV and ?F1 Antibodies
  • Combination of Anthrax-Toxin Neutralizing Antibodies: Analysis of Synergism/Antagonism Effect
  • The Efficacy of Antibiotic Treatment to Cure Guinea Pigs Intranasally Infected with Bacillus anthracis Spores
  • Reverse Vaccinology in Bacillus anthracis Bacillus anthracis
  • Role of A33R Amino-Acid 118L in the Interactions of Vaccinia Virus with the Host
  • Inhibitors of Innate Immunity from Vaccinia Virus
  • Brucella Species Synchronize Their Life Cycle to the Gestation Cycle of Their Ruminant Hosts
  • MMP-9 as a Marker for Vaccinia Virus Related Encephalitis
  • Epidemic Cowpox Virus Infections in Germany
  • The Two Partner SecretionTwo Partner Secretion Transporters of Yersinia pestis: Cloning, Immunogenicity and In Vivo Expression Following Airway Infection
  • Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX)
  • Subtyping Biothreat Bacterial Pathogens
  • A Rapid Method for Bacillus anthracis Genotyping
  • Tularemia – A Disease with an Uncertain Impact on Public Health
  • Consequences of Antibiotic Treatment of Francisella tularensis Airways Infections.-Novel Live Vaccine Candidates Against Airborne Francisella tularensis