The Hygiene Hypothesis and Darwinian Medicine

Man has moved rapidly from the hunter-gatherer environment to the living conditions of the rich industrialised countries. The hygiene hypothesis suggests that the resulting changed and reduced pattern of exposure to micro-organisms has led to disordered regulation of the immune system, and hence to...

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Bibliographic Details
Other Authors: Rook, Graham A.W. (Editor)
Format: eBook
Language:English
Published: Basel Birkhäuser 2009, 2009
Edition:1st ed. 2009
Series:Progress in Inflammation Research
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Introduction: The changing microbial environment, Darwinian medicine and the hygiene hypothesis
  • The paleolithic disease-scape, the hygiene hypothesis, and the second epidemiological transition
  • Immunoregulation by microbes and parasites in the control of allergy and autoimmunity
  • Hepatitis A virus, TIM-1 and allergy
  • Linking lifestyle with microbiota and risk of chronic inflammatory disorders
  • Soil bacteria, nitrite and the skin
  • The hygiene hypothesis and allergic disorders
  • Multiple sclerosis
  • Inflammatory bowel disease and the hygiene hypothesis: an argument for the role of helminths
  • The hygiene hypothesis and Type 1 diabetes
  • The hygiene hypothesis and affective and anxiety disorders
  • Immune regulation in atherosclerosis and the hygiene hypothesis
  • The ‘delayed infection’ (aka ‘hygiene’) hypothesis for childhood leukaemia
  • Is there room for Darwinian medicine and the hygiene hypothesis in Alzheimer pathogenesis?
  • Alternative and additional mechanisms to the hygiene hypothesis