Molecular, Clinical and Environmental Toxicology Volume 1: Molecular Toxicology
Molecular Toxicology is the first volume of a three-volume set Molecular, Clinical and Environmental Toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals in daily life. By providing intriguing insights far down to the molecular level, t...
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| Format: | eBook |
| Language: | English |
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Basel
Birkhäuser
2009, 2009
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| Edition: | 1st ed. 2009 |
| Series: | Experientia Supplementum
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| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Historical milestones and discoveries that shaped the toxicology sciences
- Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment
- The role of biotransformation and bioactivation in toxicity
- Genotoxicity: damage to DNA and its consequences
- Role of DNA repair in the protection against genotoxic stress
- On the impact of the molecule structure in chemical carcinogenesis
- Chemical induced alterations in p53 signaling
- Molecular pathways involved in cell death after chemically induced DNA damage
- The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways
- Mapping the epigenome — impact for toxicology
- Receptors mediating toxicity and their involvement in endocrine disruption
- Toxicogenomics: transcription profiling for toxicology assessment
- The role of toxicoproteomics in assessing organ specific toxicity
- High-throughput screening for analysis of in vitro toxicity