Gene Vaccines
The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion en...
| Other Authors: | , , |
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| Format: | eBook |
| Language: | English |
| Published: |
Vienna
Springer Vienna
2012, 2012
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| Edition: | 1st ed. 2012 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Preface
- 1 General mechanisms of gene vaccines
- 2 Strategies to Improve DNA Vaccine Potency: HPV-associated Cervical Cancer as a Model System
- 3 Immune-activating mechanisms of replicase-based DNA and RNA vaccines and their role in immune-apoptosis
- 4 Cytokine genes as molecular adjuvants for DNA vaccines
- 5 Pharmaceutical non-viral formulations for gene vaccines
- 6 Rational design of formulated DNA vaccines: the DermaVir approach
- 7 In vivo electroporation
- 8 Electroporation-based Trigrid™ delivery system (TDS) for DNA vaccine administration
- 9 Prime Boost Regimens for Enhancing Immunity: Magnitude, Quality of Mucosal and Systemic Gene Vaccines
- 10 Intranodal genetic immunization
- 11 Immunotherapy of cancer with RNA vaccines
- 12 DNA and RNA vaccines for prophylactic and therapeutic treatment of type I allergy
- 13 Approved veterinary vaccines – paving the way to products for human use
- 14 Current status of regulations for DNA vaccines
- 15 State of the art production of antibiotic resistance-free plasmid DNA
- 16 Industrial Manufacturing of Plasmid-DNA Products for Gene Vaccination and Therapy.