Tissue-Specific Estrogen Action Novel Mechanisms, Novel Ligands, Novel Therapies

Nuclear hormone receptors are not only important drug targets, but have also been the focus of decades of active and highly insightful research. Ten years ago, a review on nuclear receptors was entitled “The Second Decade” and a special issue of Molecular Endocrinology in 2005 dealt with the results...

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Bibliographic Details
Other Authors: Korach, Kenneth S. (Editor), Wintermantel, Tim (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 2007, 2007
Edition:1st ed. 2007
Series:Ernst Schering Foundation Symposium Proceedings
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Interfering with the Dynamics of Estrogen Receptor-Regulated Transcription
  • Actions of Estrogen and Estrogen Receptors in Nonclassical Target Tissues
  • Genetic Dissection of Estrogen Receptor Signaling In Vivo
  • Of Mice and Men: The Many Guises of Estrogens
  • Estradiol Action in Atherosclerosis and Reendothelialization
  • Functional Effects and Molecular Mechanisms of Subtype-Selective ER? and ER? Agonists in the Cardiovascular System
  • Pathogenesis and Therapy of Rheumatoid Arthritis
  • The Role of ER? and ER? in theProstate: Insights from Genetic Models and Isoform-Selective Ligands
  • Preclinical Characterization of Selective Estrogen Receptor ? Agonists: New Insights into Their Therapeutic Potential
  • Exploiting Nongenomic Estrogen Receptor-Mediated Signaling for the Development of Pathway-Selective Estrogen Receptor Ligands