Atherosclerosis: Diet and Drugs

Cardiovascular diseases continue to be the leading cause of death in the - jority of industrialized countries. The most frequent underlying pathology, namely atherosclerosis, and its clinical sequelae, namely coronary heart d- ease, cerebrovascular disease and peripheral artery disease, remain commo...

Full description

Bibliographic Details
Other Authors: Eckardstein, Arnold (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 2005, 2005
Edition:1st ed. 2005
Series:Handbook of Experimental Pharmacology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Background
  • The Pathogenesis of Atherosclerosis
  • Risk Factors for Atherosclerotic Vascular Disease
  • Metabolic Syndrome: Therapeutic Considerations
  • The Impact of Diet
  • Physical Activity, Obesity and Cardiovascular Diseases
  • Fatty Acids and Atherosclerotic Risk
  • Dietary Cholesterol, Atherosclerosis and Coronary Heart Disease
  • Plant Sterols and Stanols
  • Carbohydrates and Dietary Fiber
  • Dietary Antioxidants and Paraoxonases Against LDL Oxidation and Atherosclerosis Development
  • Soy, Isoflavones and Atherosclerosis
  • Homocysteine and B Vitamins
  • Alcohol
  • Evidence-Based Anti-Atherosclerotic Drug Therapy
  • Lipid and Non-lipid Effects of Statins
  • Fibrates
  • ACE Inhibitors and Angiotensin II Receptor Antagonists
  • Inhibition of Platelet Activation and Aggregation
  • Targets of Future Anti-Atherosclerotic Drug Therapy
  • The ABC of Hepatic and Intestinal Cholesterol Transport
  • Inhibition of the Synthesis of Apolipoprotein B-Containing Lipoproteins
  • Therapy of Hyper-Lp(a)
  • Modulation of High-Density Lipoprotein Cholesterol Metabolism and Reverse Cholesterol Transport
  • Inhibition of Lipoprotein Lipid Oxidation
  • Correction of Insulin Resistance and the Metabolic Syndrome
  • Protection of Endothelial Function
  • Modulation of Smooth Muscle Cell Proliferation and Migration: Role of Smooth Muscle Cell Heterogeneity
  • Modulation of Macrophage Function and Metabolism
  • Inflammation Is a Crucial Feature of Atherosclerosis and a Potential Target to Reduce Cardiovascular Events
  • Autoimmune Mechanisms of Atherosclerosis
  • Drug Therapies to Prevent Coronary Plaque Rupture and Erosion: Present and Future
  • Reciprocal Role of Vasculogenic Factors and Progenitor Cells in Atherogenesis
  • Gene Therapy of Atherosclerosis