Peroxisome Proliferator-Activated Receptors Discovery and Recent Advances
All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology while exhibiting differences in function, tissue distribution, and ligand specificity. In Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances, the authors trace the...
| Main Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Totowa, NJ
Humana
2013, 2013
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| Edition: | 1st ed. 2013 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Introduction.- History of PPAR Discovery: Peroxisomes
- Peroxisomal biogenesis and diseases
- Peroxisome proliferation.- Peroxisome Proliferator-Activated Receptors: Chromosomal location and gene polymorphism
- Protein structure
- PPAR Ligands: Endogenous ligands
- Exogenous PPAR modulators
- Tissue Distribution and Versatile Functions of PPARs: Neurological functions of PPARs.- PPARs and the cardiovascular system.- PPARs in pulmonary physiology and disease.- Gastrointestinal roles of PPARs.- PPAR functions in the liver.- Roles of PPARs in the pancreas.- PPARs in the urinary tract physiology and pathophysiology.- PPARs in the reproductive system
- Bone metabolism and PPARs.- Roles of PPARs in skeletal muscle biology.- Skin PPARs.- PPARs and Drug Metabolism
- Molecular Aspects of PPAR Actions: Posttranslational control of PPARs.- Mechanism of action.- Animal Models in PPAR Research.- Safety of PPAR Agonists.- The Future of PPAR Research