BLyS Ligands and Receptors

The BLyS/BAFF family of cytokines and receptors has captured and held the attention of B cell biologists during the last decade. Discovery of the two ligands and three receptors comprising this family has yielded a watershed of insights; fostering fresh paradigms in our views about the differentiati...

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Bibliographic Details
Other Authors: Cancro, Michael P. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2010, 2010
Edition:1st ed. 2010
Series:Contemporary Immunology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Description
Summary:The BLyS/BAFF family of cytokines and receptors has captured and held the attention of B cell biologists during the last decade. Discovery of the two ligands and three receptors comprising this family has yielded a watershed of insights; fostering fresh paradigms in our views about the differentiation, selection, and homeostatic control of virtually all B cell subsets. Moreover, because these processes are intimately tied to the mechanistic underpinnings of immune tolerance and activation, increased understanding of these activities promises translational progress in autoimmunity, neoplasia, and transplantation
Physical Description:XI, 284 p. 40 illus., 21 illus. in color online resource
ISBN:9781603270137