Patch-Clamp Methods and Protocols

Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training and aid the researcher in pursuing new are...

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Bibliographic Details
Other Authors: Molnar, Peter (Editor), Hickman, James J. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2007, 2007
Edition:1st ed. 2007
Series:Methods in Molecular Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Pharmacology
  • Pharmacological Analysis of Recombinant NR1a/2A and NR1a/2B NMDA Receptors Using the Whole-Cell Patch-Clamp Method
  • Memantine as an Example of a Fast, Voltage-Dependent, Open Channel N-Methyl-d-Aspartate Receptor Blocker
  • Methods for Evaluation of Positive Allosteric Modulators of Glutamate AMPA Receptors
  • Automated Voltage-Clamp Technique
  • Flip-the-Tip
  • The Roboocyte
  • Physiology
  • Infrared-Guided Laser Stimulation as a Tool for Elucidating the Synaptic Site of Expression of Long-Term Synaptic Plasticity
  • Single-Cell RT–PCR, a Technique to Decipher the Electrical, Anatomical, and Genetic Determinants of Neuronal Diversity
  • Mechanosensitive Ion Channels Investigated Simultaneously by Scanning Probe Microscopy and Patch Clamp
  • Synaptic Connectivity in Engineered Neuronal Networks
  • Modeling of Action Potential Generation in NG108-15 Cells
  • Whole-Cell Voltage Clamp on Skeletal Muscle Fibers With the Silicone-Clamp Technique
  • Determination of Channel Properties at the Unitary Level in Adult Mammalian Isolated Cardiomyocytes
  • Electrophysiological Properties of Embryonic Stem Cells During Differentiation Into Cardiomyocyte-Like Cell Types
  • Hybrid Neuronal Network Studies Under Dynamic Clamp
  • Cardiac Channelopathies Studied With the Dynamic Action Potential-Clamp Technique
  • Biophysics
  • Principles of Single-Channel Kinetic Analysis
  • Use of Xenopus Oocytes to Measure Ionic Selectivity of Pore-Forming Peptides and Ion Channels
  • Estimation of Quantal Parameters With Multiple-Probability Fluctuation Analysis