Cancer Immunotherapy Paradigms, Practice and Promise

This volume is a comprehensive discussion of the major factors affecting tumor immunology and a discussion of all major anti-cancer immunotherapeutic agents approved by the Food and Drug Administration of the United States and by European agencies. Many promising but unapproved agents in clinical tr...

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Bibliographic Details
Other Authors: Curiel, Tyler J. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2013, 2013
Edition:1st ed. 2013
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Introduction
  • Historical Perspectives and Current Trends in Cancer Immunotherapy
  • T cell and Antigen-Presenting Cell Subsets in the Tumor Microenvironment
  • Adoptive T Cell Transfer
  • Dendritic Cell-Based Cancer Immunotherapy: Achievements and novel concepts
  • Peptide and Protein-based Cancer Vaccines
  • Antigen Targeting to Dendritic Cells for Cancer Immunotherapy
  • Cytokines in the Treatment of Cancer
  • Immune Co-signaling to Treat Cance
  • Managing Regulatory T cells
  • Myeloid-Derived Suppressor Cells in Cancer: Mechanisms and therapeutic perspectives
  • Antibodies as Cancer Immunotherapy
  • Targeted Toxins in Cancer Immunotherapy
  • Miscellaneous Approaches and Considerations: TLR agonists and other inflammatory agents, anti-chemokine agents, infectious agents, tumor stroma targeting, age and sex effects, and miscellaneous small molecules
  • Issues in Pre-clinical Models, Clinical Trial Design and Analytical Considerations in Developing and Evaluating Novel Cancer Immunotherapies
  • Monitoring Antigen-Specific Responses in Clinical Trials of Immunotherapy
  • Index