Formulating Poorly Water Soluble Drugs
A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced ana...
| Other Authors: | , , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2012, 2012
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| Edition: | 1st ed. 2012 |
| Series: | AAPS Advances in the Pharmaceutical Sciences Series
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Route-Specific Challenges in Delivery of Poorly Water Soluble Drugs
- Optimizing the Formulation of Poorly Water Soluble Drugs
- Solid-State Techniques for Improving Solubility
- Mechanical Particle Size Reduction Techniques
- Solubilized Formulations
- Injectable Formulations of Poorly Water Soluble Drugs
- Design and Development of Self-Emulsifying Lipid Formulations for Improving Oral Bioavailability of Poorly Water-Soluble and Lipophilic Drugs
- Structured Development Approach for Amorphous Systems
- Melt Extrusion
- Spray Drying Technology
- Pharmaceutical Cryogenic Technologies
- Precipitation Technologies for Nanoparticle Production
- Emerging Technologies to Increase the Bioavailability of Poorly Water Soluble Drugs
- Regulatory Considerations for Development and Commercialization of Poorly Water Soluble Drugs