TH17 Cells in Health and Disease

“About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation.   However, TH1 /...

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Bibliographic Details
Other Authors: Jiang, Shuiping (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2011, 2011
Edition:1st ed. 2011
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • From Th1/Th2 Pardigm to Th17 cells: Le Roi est Mort, Vive le Roi
  • Th17 Cytokines: Characteristics, Regulation, Biological Function
  • TGF-beta and Th17 cells
  • A Pleiotropic Cytokine and Th17 cells
  • Apoptosis and Th17 cell Differentiation
  • IL-1 and Innate Immunity in the Differentiation of Th17 cells. Negative Regulation of Th17 Differentiation
  • Signal Transduction in Th17 cell Differentiation
  • Structure and IL-17 Receptor Signaling
  • Trafficking Receptors and Migration of Th17 cell Subsets
  • Plastic T cells: Recycling Effector Functions
  • Human Th17 cells
  • Th17 Cytokines in Primary Mucosal Immunity
  • Th17 cells and IL-23 in Gut Inflammation
  • The Roles of IL17A and IL17F in Mucosal Infection and Allergy
  • Th17 cells in Fungal Infections
  • IL-17 cells in Organ Transplantation Rejection and Tolerance
  • Th17 cells, Proteins Associated with Th17 Polarization, and their Role in Graft versus Host Disease
  • Interplay of Pathogenic Th1/Th17 cells and Regulatory T cells in Auto-immune Disease: A tale of Yin and Yang
  • The Role of Interleukin-17 in Systemic Lupus Erythematosus
  • IL-17 in B cell Biology and Systemic Lupus Erythematosus
  • IL-17 and Th17 cells in Human Rheumatoid Arthritis
  • The Role of IL-23/Th17 Immune Pathway in the Pathogenesis of Arthritis
  • The Roles of IL-22 and its Related Family Members in the Pathogenesis of Psoriasis
  • Th17 Pathway in Psoriasis and INflammatory Skin Diseases
  • Th17 cells in the Tumor Micro-environment
  • IL-17-producing NKT cells in Airway Inflammation
  • IL-17-producing T cells in Auto-immune Disease