Targeting the Wnt Pathway in Cancer
In this book, we highlight the recent advances in our understanding of the complexity of the Wnt pathway, particularly its intricate regulation and cross-talk with other key signal transduction pathways in normal and tumor cells. As a way to comprehend the role of Wnt pathway activation in tumor ini...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2011, 2011
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| Edition: | 1st ed. 2011 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- An Introduction to Wnt Signaling.- Regulation of Wnt Secretion and Distribution
- Wnt Signaling in Stem Cells
- Crosstalk of the Wnt Signaling Pathway
- Dysregulation of the WNT Pathway in Solid Tumors.- WNT/b-catenin Signaling in Leukemia
- Use of Genetically-engineered Mouse Models in Identification and Validation of Therapeutic Targets for Colon Cancer
- Targeting Wnt Signalling in Cancer
- Inhibiting the Wnt Signaling Pathway with Small Molecules.- Targeting of Wnt Signaling Inside the Nucleus.-