Inflammation and Retinal Disease: Complement Biology and Pathology
Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical cand...
| Other Authors: | , |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
2010, 2010
|
| Edition: | 1st ed. 2010 |
| Series: | Advances in Experimental Medicine and Biology
|
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- The Case for Complement and Inflammation in AMD: Open Questions
- The Role of Complement in AMD
- Multiple Interactions of Complement Factor H with Its Ligands in Solution: A Progress Report
- Genetic Control of Complement Activation in Humans and Age Related Macular Degeneration
- Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration
- The Role of the Classical Complement Cascade in Synapse Loss During Development and Glaucoma
- A Role for Complement in Glaucoma?
- The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease
- Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration
- A Targeted Inhibitor of the Complement Alternative Pathway Reduces RPE Injury and Angiogenesis in Models of Age-Related Macular Degeneration
- Complement Depletion with Humanized Cobra Venom Factor in a Mouse Model of Age-Related Macular Degeneration