Drug Discovery in Pancreatic Cancer Models and Techniques

Over the past two decades, tremendous advances have been made in the field of cancer drug discovery, particularly in the area of molecular and genetic models and technologies, many of which have been or are beginning to be applied to the drug discovery process for pancreatic cancer. Drug Discovery i...

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Bibliographic Details
Other Authors: Han, Haiyong (Editor), Grippo, Paul (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2010, 2010
Edition:1st ed. 2010
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Drug Evaluations in Pancreatic Cancer Culture Systems
  • Mouse Xenograft Models for Drug Discovery in Pancreatic Cancer
  • Fluorescent Metastatic Mouse Models of Pancreatic Cancer for Drug Discovery
  • A New Preclinical Paradigm for Pancreas Cancer
  • Zebrafish as a Biological System for Identifying and Validating Therapeutic Targets and Compounds
  • Gene Expression Arrays in Pancreatic Cancer Drug Discovery Research
  • Using Array Comparative Genomic Hybridization of Pancreatic Cancer Samples to Map Interesting Regions for Target Gene Identification
  • The Application of High-Throughput RNAi in Pancreatic Cancer Target Discovery and Drug Development
  • MicroRNA Profiling and Its Application in Drug Discovery in Pancreatic Cancer
  • Methylation Detection and Epigenomics in Pancreatic Cancer
  • Tissue Microarray Applications in Drug Discovery for Pancreatic Cancer
  • Proteomic Analysis of Blood and Pancreatic Juice
  • Applications of Antibody-Lectin Sandwich Arrays (ALSA) to Pancreatic Cancer Diagnostics and Drug Discovery
  • The Development of Pharmacodynamic Endpoint Models for Evaluation of Therapeutics in Pancreatic Cancer