Structure-based Drug Discovery

Discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission. Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of...

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Bibliographic Details
Other Authors: Jhoti, Harren (Editor), Leach, Andrew R. (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 2007, 2007
Edition:1st ed. 2007
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis
  • Protein Production for Structural Genomics - Strategies for the Next Phase
  • to Fragment Screening
  • Fragment-Based NMR Screening in Lead Discovery
  • Fragment-Based Screening by X-ray Crystallography
  • Scaffold-Based Drug Discovery
  • Biophysical Methods
  • Illustration of Current Challenges in Molecular Docking
  • Scoring Functions