Analyzing T Cell Responses How to analyze cellular immune responses against tumor associated antigens
Active specific immunotherapy is a promising but investigational modality in the management of cancer patients. Currently, several different cancer vaccine formulations such as peptides, proteins, antigen-pulsed dendritic cells, whole tumor cells, etc. in combination with various adjuvants and carri...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Dordrecht
Springer Netherlands
2005, 2005
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| Edition: | 1st ed. 2005 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Monitoring Antigen-Specific T Cell Responses
- Tumor Associated Antigens
- Immune Escape, Tumor induced immune suppression and immune escape: Mechanisms and Possible Solutions
- Virus Specific T-Cell Responses
- Cytotoxicity Assays Killer Lymphocytes in Cancer
- Monitoring T Cell Proliferation
- Elispot Assay, Assessment of Cellular Immune Responses to Anti-Cancer Vaccines
- Modified Elispot, Modifications of the Elispot Assay for T Cell Monitoring in Cancer Vaccine Trials
- Intracellular Cytokine Staining, Cytokine flow cytometry for characterization of tumor-specific T cell responses
- Cytometric Cytokine Secretion Assay, Detection and Isolation of Antigen-Specific T Cells
- Peptide/MHC Tetramer Analysis
- In Situ MHC Tetramer Staining, In Situ Tetramers
- MHC-IG Dimeric Molecules, Dimers - MHC-IG dimeric molecules for the analysis of antigen-specific T cell responses
- TCR Analyses, T-cell receptor CDR3 analysis: Molecular fingerprinting of the T-cell receptor repertoire
- Peptide/HLA-GFP Complexes, Detection of Antigen-Specific T Cells by Acquisition of Peptide/Hla-Gfp Complexes
- QRT-PCR, Quantitative RT-PCR for the Analysis of T cell Responses in Immunized Cancer Patients
- Microarrays, Gene expression profiling approaches for the monitoring of anti-cancer immune responses
- Concluding Remarks