Pancreatic Cancer

Worldwide, there are an estimated 232, 000 new cases of pancreatic cancer annually. In the United States, it is the fourth leading cause of cancer death, and approximately 30,000 people die of pancreatic cancer each year. The disease is difficult to diagnose in its early stages, and most patients ha...

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Bibliographic Details
Other Authors: Neoptolemos, John P. (Editor), Urrutia, Raul A. (Editor), Abbruzzese, James (Editor), Büchler, Markus W. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2010, 2010
Edition:1st ed. 2010
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Epidemiology: world overview, risk factors, prospects for prevention
  • Development and structure of pancreas
  • Pathologic classification and biological behaviour of pancreatic neoplasia
  • Developmental molecular biology of the pancreas
  • Molecular pathology of precursor lesions of pancreatic cancer, pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm (MCN)
  • Epigenetics: its fundamentals and applications to a revised comprehensive progression model for pancreatic cancer
  • Molecular pathology of pancreatic neuroendocrine tumours MEN-1: gastrinomas, insulinoma, Non-Functioning Tumours, VIPoma, glucagonoma, Von Hippel-Lindau, Neurofibromatosis
  • Sporadic neuroendocrine pancreatic tumours
  • Molecular pathology of non-pancreatic cancer lesions: Ampullary cancer, intra-pancreatic bile duct cancer, and duodenal cancer
  • Miscellaneous non-pancreatic non-endocrine tumours
  • Inherited endocrine pancreatic tumors associated with Multiple Endocrine Neoplasia Type 1 Von-Hippel-Lindau Syndrome, and Neurofibromatosis Type 1
  • Clinical decision making in pancreatic cancer
  • Paraneoplastic syndromes
  • Diagnostic and therapeutic response markers
  • CT and fusion PET-CT Diagnosis, staging, and follow-up
  • MRI and MRCP: diagnosis and staging of pancreatic cancer
  • EUS Diagnosis and staging
  • Laparoscopy and laparoscopic ultrasound: diagnosis and staging
  • Overview of palliative management for pancreatic cancer
  • Endoscopy
  • Interventional radiology
  • Role of palliative surgery in advanced pancreatic cancer
  • Chemotherapy for advanced pancreatic cancer
  • Developments in chemoradiation in advanced pancreatic cancer
  • Surgical resection for pancreatic cancer
  • Role of venous resection in pancreatic cancer surgery
  • Pathological reporting and staging following resection
  • Japanese Pancreas Society staging for pancreatic cancer
  • Adjuvant chemotherapy in pancreatic cancer
  • Case for adjuvant chemoradiation therapy for pancreatic cancer
  • Case for neoadjuvant treatment in pancreatic cancer
  • Borderline resectable disease
  • Management of cystic neoplasms serous cystic neoplasms mucinous, cystic neoplasms, intraductal paillary mucinous neoplasms
  • Laparoscopic surgery for pancreatic neoplasm
  • Modern Japanese approach to pancreas cancer
  • Development of novel biomarkers
  • Inherited genetics of pancreatic cancer and secondary screening
  • Gene therapy for pancreatic cancer
  • Vaccine therapy and immunotherapy
  • Emerging targets in pancreatic cancer.-
  • Novel molecular relationships between chronic pancreatitis and cancer
  • Pancreatic cancer stem cells
  • Cell cycle control: signalling pathways in pancreatic pathogenesis
  • Apoptosis: signalling pathways in pancreatic pathogenesis
  • EGFR: signalling pathways in pancreatic pathogenesis Pl3, Akt, lKK, Ras, Raf, MAPKK, ERK
  • Hedgehog: signalling pathways in pancreatic pathogenesis
  • Smad4/TGF-ß pathway: signalling pathways in pancreatic pathogenesis
  • Notch signalling in pancreatic morphogenesis and pancreatic cancer
  • Molecular characterization of pancreatic cell lines
  • Mouse models of exocrine pancreatic cancer
  • Principles and applications of microarray gene expression in pancreatic cancer
  • Principles and applications of proteomics in pancreatic cancer
  • Tumour-stromal interaction: invasion and metastases
  • Genetic susceptibility, high risk groups, chronic and hereditary pancreatitis, familial pancreatic cancer syndromes