Actin-Binding Proteins and Disease

This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin,...

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Bibliographic Details
Other Authors: dos Remedios, Cris (Editor), Chhabra, Deepak (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2008, 2008
Edition:1st ed. 2008
Series:Protein Reviews
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
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245 0 0 |a Actin-Binding Proteins and Disease  |h Elektronische Ressource  |c edited by Cris dos Remedios, Deepak Chhabra 
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260 |a New York, NY  |b Springer New York  |c 2008, 2008 
300 |a XIV, 348 p. 52 illus., 22 illus. in color  |b online resource 
505 0 |a Actin -- Actin: An Overview of Its Structure and Function -- Actin Genetic Diseases -- Actin-Binding Drugs: An Elegant Tool to Dissect Subcellular Processes in Endothelial and Cancer Cells -- Autoantigenicity of Actin -- Actin-Binding Proteins -- Overview: Actin-Binding Protein Function and Its Relation to Disease Pathology -- ADF/Cofilin, Actin Dynamics, and Disease -- Gelsolin and Disease -- Profilin -- The Roles of Thymosin ?4 in Cell Migration and Cell-to-Cell Signaling in Disease -- Actin-Binding Proteins -- Actin and Actin-Binding Proteins in Cancer Progression and Metastasis -- Diseases with Abnormal Actin and Actin-Binding Proteins in Leukocyte and Nonmuscle Cells -- The Role of PIP2 in Actin, Actin-Binding Proteins and Disease -- Intracellular Pathogens and the Actin Cytoskeleton -- Actin and Its Binding Proteins in Heart Failure 
653 |a Cell Biology 
653 |a Protein Biochemistry 
653 |a Cytology 
653 |a Biochemistry 
653 |a Proteins  
700 1 |a Chhabra, Deepak  |e [editor] 
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490 0 |a Protein Reviews 
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520 |a This volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics