Mouse Models of Human Blood Cancers Basic Research and Pre-clinical Applications

Although it remains an open question among some people whether mice and humans are similar in disease development, the laboratory mouse has emerged as the preeminent animal model for human diseases. This is underscored by the recently completed mouse and human genome projects, which have revealed th...

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Bibliographic Details
Other Authors: Li, Shaoguang (Editor)
Format: eBook
Language:English
Published: New York, NY Springer New York 2008, 2008
Edition:1st ed. 2008
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Insights into Pathophysiology and Therapy
  • Genetic Modeling of Human Blood Cancers in Mice
  • Murine Models of Hematopoietic Disease: Pathologic Analysis and Characterization
  • Mechanisms of DNA Double-Strand Break Repair in Hematopoietic Homeostasis and Oncogenesis
  • Modeling Human Leukemia Using Immune-Compromised Mice
  • Dietary Restriction: A Model System Probing the Cell Fate Decision Between Cancer and Senescence
  • Modeling Human Philadelphia Chromosome-Positive Leukemia in Mice
  • Mouse Models of Human Mature B-Cell and Plasma Cell Neoplasms
  • Genetic and Virological Predisposition to Pre-B Lymphomagenesis in SL/Kh
  • Animal Cancer Models in Anticancer Drug Discovery and Development
  • DGL Global Strategies in DNA Microarray Gene Expression Analysis and Data Mining for Human Blood Cancers