Cardiac Drug Development Guide

The revolution in molecular medicine makes it imperative to integrate the classical and molecular approaches to drug development for the treatment of heart disease, the number one killer in North America and Europe. In the Cardiac Drug Development Guide, basic medical researchers, clinicians, and ph...

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Bibliographic Details
Other Authors: Pugsley, Michael K. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana Press 2003, 2003
Edition:1st ed. 2003
Series:Methods in Pharmacology and Toxicology
Subjects:
Online Access:
Collection: Springer Protocols Archive 1981-2004 - Collection details see MPG.ReNa
Table of Contents:
  • Cardiac Drug Development
  • Novel Molecular Targets for Cardiac Drug Development
  • The Role of Cardiac Pacemaker Currents in Antiarrhythmic Drug Discovery
  • Oxygen Free Radicals in Heart Disease
  • Mitogen-Activated Protein Kinases-Mediated Signaling in Cardiac Pathology
  • Development of Anti-Inflammatory Drugs for Cardiovascular Disease
  • Development and Use of Platelet Glycoprotein Antagonists in Heart Disease
  • The Sodium-Hydrogen Exchange System in the Heart
  • Nitric Oxide and Cardiac Ischemia
  • Functional Endpoints Evaluating Cardiac Drug Activity
  • Ionic Mechanisms of Atrial Fibrillation
  • Targeting Ischemic Ventricular Arrhythmias
  • Biochemical Mediators of Ventricular Arrhythmias in Ischemic Heart Disease
  • Heterologous Expression Systems and Screening Technologies in Ion Channel Drug Discovery
  • Molecular Diversity of Ion Channels in the Mouse Heart
  • Delayed Protection of the Myocardium
  • Clinical Aspects in Cardiac Drug Development
  • Cardiac Troponin Testing for Detection of Myocardial Infarction
  • A Genetic Basis for Cardiac Arrhythmias
  • Myocardial Adenoviral Vector Delivery for Cardiovascular Gene Therapy
  • The Role of Pharmacometrics in Cardiovascular Drug Development
  • Gender Differences in Heart Failure
  • Angiogenesis Therapies for Coronary Artery Disease