Melanoma Techniques and Protocols Molecular Diagnosis, Treatment, and Monitoring

With the completion of the Human Genome Project, it is now possible to decipher the biochemical cascade of events that lead to melanoma, a virulent form of cancer that is currently at epidemic proportions worldwide. In Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment, and Monitoring...

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Bibliographic Details
Other Authors: Nickoloff, Brian J. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana Press 2001, 2001
Edition:1st ed. 2001
Series:Methods in Molecular Medicine
Subjects:
Online Access:
Collection: Springer Protocols Archive 1981-2004 - Collection details see MPG.ReNa
Table of Contents:
  • Biology
  • The Many Molecular Mysteries of Melanoma
  • Isolation of Tumor Suppressor Genes in Melanoma by cDNA Microarray
  • Molecular Characterization of Melanoma-Derived Antigens
  • Experimental Induction of Human Atypical Melanocytic Lesions and Melanoma in Ultraviolet-Irradiated Human Skin Grafted to Immunodeficient Mice
  • Dissection of Immunosuppressive Effects of Ultraviolet Radiation
  • Antisense Oligonucleotides as Research Tools
  • Diagnosis
  • Genetic Testing in Familial Melanoma
  • Role of Molecular Biology in Diagnostic Pathology of Melanoma
  • Identification of Altered Gene Expression Associated with Pigmentary Lesions by Differential Display Analysis
  • Fluorescence In Situ Hybridization as a Tool in Molecular Diagnostics of Melanoma
  • Treatment
  • Antigen-Pulsed Dendritic Cell Approach to Melanoma
  • Gene Therapy in Melanoma
  • Use of Gene Gun for Genetic Immunotherapy
  • Role of Cytokines in Pathology of Melanoma and Use of Biologic Response Modifiers in Melanoma
  • Surgical Techniques for Treatment of Primary Cutaneous Melanoma
  • Monitoring
  • Utility of Fine-Needle Aspiration Biopsy for Prospective Analysis of Patients Undergoing Therapy for Metastatic Melanoma
  • A Molecular Technique Useful in the Detection of Occult Metastases in Patients with Melanoma
  • Immunoscope Analysis of T-Lymphocytes Infiltrating Melanocytic Tumors
  • T-Cell Receptor Clonotype Mapping Using Denaturing Gradient Gel Electrophoresis
  • Methods for Use of Peptide-MHCTetramers in Tumor Immunology