Aging Methods and Protocols

With rapidly rising life expectancies and a general lack of understanding about the aging process, the need to treat geriatric diseases is becoming an ever more significant private and public health issue. In Aging Methods and Protocols, Yvonne and Christopher Barnett and a team of recognized intern...

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Bibliographic Details
Other Authors: Barnett, Yvonne A. (Editor), Barnett, Christopher R. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana Press 2000, 2000
Edition:1st ed. 2000
Series:Methods in Molecular Medicine
Subjects:
Online Access:
Collection: Springer Protocols Archive 1981-2004 - Collection details see MPG.ReNa
Table of Contents:
  • The Study of Cell Senescence and Cell Death
  • Understanding Aging
  • Use of the Fibroblast Model in the Study of Cellular Senescence
  • Human T-Cell Clones
  • Telomeres and Replicative Senescence
  • Detection of Molecular Events During Apoptosis by Flow Cytometry
  • Raf-1 Protein Kinase Activity in T Cells from Aged Mice
  • Identification of Differentially Expressed Genes in Young and Senescent T Cells
  • Age-Related Changes to Xenobiotic Metabolizing Enzyme Systems
  • Xenobiotic-Metabolizing Enzyme Systems and Aging
  • Age-Related Changes to Defense Systems Against Biomolecule Damage
  • Assessing Age-Related Changes in Antioxidant Status
  • Measurement of DNA Damage and Repair Capacity as a Function of Age Using the Comet Assay
  • Measurement of DNA Damage and Repair in Human White Blood Cells by an Immunochemical Assay
  • Age-Related Changes to Cellular Biomolecules
  • Measurement of 8-Oxo-deoxyguanosine in Lymphocytes, Cultured Cells, and Tissue Samples by HPLC with Electrochemical Detection
  • Mutation and the Aging Process
  • Somatic Mutations and Aging
  • Assessment of Susceptibility of Low-Density Lipoprotein to Oxidation
  • Measurement of Pentosidine in Biological Samples
  • Mitochondrial Morphology, Function, and Mutation with Age
  • Causes and Consequences of Damage to Mitochondria
  • Causes and Consequences of Damage to Mitochondria
  • Analysis of Mitochondrial DNA Mutations
  • Analysis of Mitochondrial DNA Mutations
  • Immune System and Aging
  • Assessment of T-Cell Function in the Aged
  • Dendritic Cells in Old Age
  • Age-Related Alterations to Natural Killer Cell Function
  • Immunogenetics and Life-Span
  • Case Studies
  • Dietary Restriction and Life-Span Extension
  • The Use of Genetically Engineered Mice in Aging Research