Mary Sutherland may refer to:
* Mary S. Sutherland, American academic and educator; professor of health education at Florida State University
* Mary Ann Sutherland (1864–1948), New Zealand farmer and landowner
* Mary Sutherland (forester) (1893–1955), first professional woman employed by the New Zealand State Forest Service
* Mary Sutherland (political administrator) (1895–1972), Chief Women's Officer of the British Labour Party
* Mary Sutherland Maxwell, birth name of Rúhíyyih Khánum (1910–2000), American-born Canadian Hand of the Cause of the Baháʼí Faith
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