1 “... death (5/10,000), gallbladder disease (20/10,000), dementia (22/10,000), and urinary incontinence (872...”

2 “... Trials; references of relevant publications, government Web sites. STUDY SELECTION: English-language...”

3 “... Trials; references of relevant publications, government Web sites. STUDY SELECTION: English-language...”

4

5

6

7 “... (RESULTS): Fifty total studies (30 trials and 20 cohort studies) with a total of 94,168 participants were...”

8 “... SELECTION: Two investigators independently selected English-language studies using a priori criteria....”

9 “... SELECTION: Two investigators independently selected English-language studies using a priori criteria....”

10 “... impairment could achieve visual acuity of 20/40 or better with refractive correction. Based on numerous...”

11 “... impairment could achieve visual acuity of 20/40 or better with refractive correction. Based on numerous...”

12 “... to identify ongoing trials. We conducted ongoing surveillance through November 22, 2017 to identify any major...”

13 “... to identify ongoing trials. We conducted ongoing surveillance through November 22, 2017 to identify any major...”

14 “... were excluded from the analysis (2.0% vs. 0.9%, p=0.04); almost all lung cancers occurred in former...”

15 “... (pooled RR, 4.22 [95% CI, 2.21 to 8.06], N=7,339). LIMITATIONS: Tests for the direct diagnosis of LTBI...”

16 “... from the PLCO and ERSPC trials imply that between 20.7 percent and 50.4 percent of screen-detected...”

17 “... from the PLCO and ERSPC trials imply that between 20.7 percent and 50.4 percent of screen-detected...”

18 “..., 1.11 to 1.33]; k=22; n=8,246) and at 3 to less than 6 months (RR, 1.20 [95% CI, 1.05 to 1.38]; k=18; n...”