1 Table of Contents: “... in aging and longevity -- Overview of PARP Inhibitor Design and Optimization -- Structure Based Design...”

2 Subjects: “...PARP inhibitor...”

3 Subjects: “...PARP inhibitor...”

4 Subjects: “...PARP inhibitor resistance...”

5 Subjects: “...PARP inhibitors...”

6 Subjects: “...PARP inhibitor...”

7 Subjects: “...PARP-inhibitor...”

8 Subjects: “...PARP inhibitor...”

9 Table of Contents: “...Evolution of the development of PARP inhibitors -- Exploiting cancer synthetic lethality in cancer...”

10 Table of Contents: “...In Vitro Long Term Proliferation Assays to Study Antiproliferative Effectsof PARP Inhibitors...”

11 Table of Contents: “... -- The concept of synthetic lethality -- Exploiting DNA repair mechanisms for cancer therapy -- PARP inhibitors...”

12 Table of Contents: “... -- Olaparib -- Mediola -- PARP inhibitors...”

13 “... promising results, including poly (ADP-ribose) polymerase (PARP) inhibitors, anti-Notch ligand Delta-like...”

14 Table of Contents: “...: Overview in Genomic analysis and Clinical Context -- 18 PARP Inhibitors-Mechanism of action -- 19 PARPi...”

15 Table of Contents: “... Analysis -- Regulation of Chromatin Structure by PARP-1 -- The Use of PARP Inhibitors in Cancer Therapy...”

16 Table of Contents: “... Cancer -- Role of PARP Inhibitors in Triple Negative Breast Cancer (TNBC) -- Targeted Therapies...”

17 Table of Contents: “... of Inflammation and Circulatory Shock -- Role of Poly-ADP-Ribosylation in Cancer Development -- PARP Inhibitors...”

18 “... provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally...”

19 Table of Contents: “.../mTOR Pathway in Prostate Cancer -- PARP Inhibitors -- Targeting C-Met/VEGF in Castration Resistant...”

20 Table of Contents: “... Alkyltransferase -- 8 Cellular Protection Against the Antitumor Drug Bleomycin -- 9 Potential Role of PARP...”