1 Table of Contents: “...Summary measures: mean, variance, covariance and correlation -- Fundamentals of statistics: models...”

2 Table of Contents: “...Statistics is a vital tool in microarray studies -- From formulating the research questions, via...”

3 Table of Contents: “...Tag SNPs and multi-marker predictors -- The general problem of imputing genotypes for association...”

4 Table of Contents: “...General concepts of sample size calculation -- Group sequential designs -- Pocock method -- O'Brien...”

5 Table of Contents: “... to be considered and addressed prior to starting an adaptive design -- Examples & general check list on designing...”

6 Table of Contents: “...The general problem of imputation -- Testing imputed SNPs for association -- Examples of imputation...”

7 Table of Contents: “...-MS metabolomics -- Peak alignment -- Warping: some general considerations -- Missing values -- Sample...”

8 Table of Contents: “... problem -- Haplotype determination options -- Statistical estimation of haplotypes -- General framework...”

9 Table of Contents: “...Genetic admixture processes -- Statistical approach to allele frequencies in admixed populations...”

10 Table of Contents: “...Historical antecedents to the clinical trial -- Pharmacology & mathematical statistics as key...”

11 Table of Contents: “... biology -- Many of the statistical methods used in quantitative genetics have been adopted for general use...”