1 Table of Contents: “...Contents: Mismatch repair (MMR) -- Lynch syndrome -- Microsatellite instability (MSI) -- Colorectal...”

2

3 Table of Contents: “...Lynch syndrome (underlying single gene defect) -- Microsatellites -- Important genes containing...”

4 Table of Contents: “...Contents: Genetic testing -- Ethical issues -- Clinical scenarios of genetic testing -- Lynch...”

5 Table of Contents: “..., ovarian, and colorectal -- Implication of BRCA1/2 in ovary and breast cancers -- Colon cancer and Lynch...”

6 Table of Contents: “... and sales -- Patent cliff -- Quality by design -- Product pricing -- Drug launch time -- Lifecycle...”

7 Table of Contents: “... -- Effective way of reducing the cost of healthcare -- Launching new products -- EU countries and mechanisms...”