1 Table of Contents: “...Why now? -- What would a knowledge network and new taxonomy look like? -- How do we get...”

2 Table of Contents: “... oversight: finding the balance -- Applying and using new tools and knowledge safely -- Collaboration...”

3 “... progress toward real-time knowledge generation through the seamless integration of clinical practice...”

4 “..., and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding...”

5 “... evidence; identification of existing knowledge and research gaps; authorship expertise; and, if applicable...”

6 “... and unsuccessful clinical development programs; new knowledge about the genetic underpinnings of brain disorders...”

7 “... knowledge upon which to develop new agents have provided incentives for alternative approaches to drug...”

8