1 Table of Contents: “... -- The role of toxicoproteomics in assessing organ specific toxicity -- High-throughput screening for analysis...”

2 Table of Contents: “...-Response Analysis to Inform Regulatory Decision-Making...”

3 Table of Contents: “... -- Mechanistic Models of Physiological Control Systems -- Foundations of Pharmacodynamic Systems Analysis...”

4 Table of Contents: “... Chemicals -- Role of Computational Methods in Pharmaceutical Sciences -- Best Practices in Mathematical...”

5 Table of Contents: “... Processes -- Mathematical Tools for the Quantitative Definition of a Design Space -- Optimization...”

6 Table of Contents: “... to Mathematical Modeling -- Enzyme-Linked Immunosorbent Assay to Quantify Targeting Molecules on Nanoparticles...”

7 Table of Contents: “... -- 21 Critical Quality Attributes, Specifications, and Control Strategy -- 22 Multivariate Analysis...”

8 Table of Contents: “... Verification -- Toxicological Assessment Via Gene Network Analysis -- Weaving Knowledge into Biological...”

9 Table of Contents: “... for small Molecule biomarkers -- Cell-based Assays -- New Technologies for Cellular Analysis -- Flow...”

10 Table of Contents: “... Analysis System Utilizing Open-Source Software -- Systems Toxicology from Genes to Organs -- Agent Based...”

11 Table of Contents: “... & Equipment -- Multivariate Analysis for Process Understanding, Continuous Process Verification and Condition...”

12 Table of Contents: “... of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) -- Western Blot Analysis -- Application of Reverse Transcription...”

13 Table of Contents: “...: statistical aspects, standardisation, elementary analysis -- Measuring bioactivity: Ki, IC50 and EC50...”

14 Table of Contents: “... Kinetic Analysis of P-gp Mediated Transport Through Confluent Cell Monolayers -- Systems Biology...”