1 “... therapeutic regimens, cancer may still relapse as refractory and metastatic cancer. Therefore, further...”

2 Table of Contents: “... -- Chapter 7: Conflicts, relapse and failure in the sustainability process - neglected problems -- Part III...”

3 “... cells as a valuable target to eradicate tumor relapse; Spheroids in preclinical model for cancer...”

4 “... immunomodulatory drugs, proteasome inhibitors, and monoclonal antibodies, in relapsed/refractory disease and a...”

5 “... and functional, of osteosarcoma dramatically improved in the 1980s, the prognoses of the patients with relapsed...”

6 “... for the unfavorable prognosis and of relapses even after initially successful tumor therapies. The lack of success...”