1 Table of Contents: “... -- The Monitoring and Reporting of Clinical Trials -- Economic Evaluation in the Critical Care Literature -- Ethical...”

2 Table of Contents: “...Sepsis -- Infection and the Host Septic Response: Implications for Clinical Trials of Mediator...”

3 Table of Contents: “... Regulators of the Immune Response -- Sepsis: Clinical Aspects -- Severe Sepsis in the Elderly...”

4 Table of Contents: “...Endocrine Response after Brain Injury -- The Value of Hemodynamic Measurements in the Early Stage...”

5 Table of Contents: “... improvement programs: from evidence towards clinical implementation...”

6 Table of Contents: “...Gut Permeability: Mechanisms, Measurement and Clinical Applications -- Possible Therapeutic...”

7 Table of Contents: “... Augmentation of Endogenous Neuroprotective Responses after Traumatic Brain Injury -- Experimental and Clinical...”

8 Table of Contents: “... and Massive Bleeding -- Neuromuscular Considerations -- Rapid Response Teams -- Data Management...”

9 Table of Contents: “...Cellular Responses in Sepsis -- Cellular Dysfunction -- Cardiovascular Dysfunction -- Hemodynamic...”

10 Table of Contents: “...Cellular Responses in Sepsis -- Cellular Dysfunction -- Cardiovascular Dysfunction -- Hemodynamic...”

11 Table of Contents: “...Genomics and Proteomics -- Inflammatory Response -- Current and Future Management Sepsis...”

12 Table of Contents: “... Responsiveness (Xavier Monnet) -- Chapter 24. Pulmonary Arterial Catheter (Didier Payen) -- Chapter 25. Arterial...”

13 Table of Contents: “... Medicine -- Health Economics in Intensive Care -- Ethical Implications of Standardizing Clinical Decisions...”

14 Table of Contents: “... immune response using cytomics -- Precision medicine in septic shock -- Part II. Sepsis Biomarkers...”

15 Table of Contents: “... Cardiorespiratory Instability -- Long-termOutcomes after Critical Illness Relevant to Randomized Clinical Trials...”

16 Table of Contents: “... Response to Heart Failure -- Infectious Causes of Acute Cardiac Dysfunction -- Heart Failure in Septic...”

17 Table of Contents: “... with novel clinical applications.-ARDS subphenotypes: understanding a heterogeneous syndrome -- Assessment...”

18 Table of Contents: “... -- Cellular Response to Inflammation and its Antagonism by ?2-Adrenoceptor Agonists -- Sepsis Treatment...”

19 Table of Contents: “... Sepsis: Organ Failure Scores, PIRO or Both? -- Critical Care Outreach -- On the Response to Acutely...”

20 Table of Contents: “... -- Intra-aortic Balloon Counterpulsation in Cardiogenic Shock -- IV Inflammatory Responses in the Lung...”