1 Subjects: “...Clinical Trials as Topic...”

2 “... of practice-based interventions. Settings of care for included studies, although rarely characterized...”

3 “... of practice-based interventions. Settings of care for included studies, although rarely characterized...”

4

5

6 “... observational studies of pregnant women receiving antidepressants for mixed or unreported reasons compared...”

7 “... observational studies of pregnant women receiving antidepressants for mixed or unreported reasons compared...”

8 “... comparative trials. The studies were conducted in the United States, Canada, United Kingdom, New Zealand...”

9 “... comparative trials. The studies were conducted in the United States, Canada, United Kingdom, New Zealand...”

10 “... randomized subjects, practices, or providers to screening and a comparator, and none of the included studies...”

11 “... randomized subjects, practices, or providers to screening and a comparator, and none of the included studies...”

12

13

14 “... [MD], −0.94 [95% CI, −1.40 to −0.48]; I2 16%). There was not evidence of small study effects. Meta...”

15 “... [MD], −0.94 [95% CI, −1.40 to −0.48]; I2 16%). There was not evidence of small study effects. Meta...”

16 “... disorder symptoms. We included related publications and an additional four studies to address harms...”

17 “... disorder symptoms. We included related publications and an additional four studies to address harms...”

18 “...), Scopus, and the Cochrane Clinical Trials Registry through August 2014 plus reference lists of included...”

19 “...), Scopus, and the Cochrane Clinical Trials Registry through August 2014 plus reference lists of included...”

20 “... primarily pre/post studies whose inherent high risk of bias precludes drawing inferences of causality...”