1

2

3 “... examination as a one-time or periodic screening test. In addition, there is limited evidence regarding...”

4 “... examination as a one-time or periodic screening test. In addition, there is limited evidence regarding...”

5 “... news Web sites and journal tables of contents to identify potentially eligible trials. Two...”

6 “... program, and one showed a statistically nonsignificant adverse effect on depression remission. CONCLUSIONS...”

7 “... program, and one showed a statistically nonsignificant adverse effect on depression remission. CONCLUSIONS...”

8 “... news Web sites and journal tables of contents to identify potentially eligible trials. Two...”

9 “... to the effectiveness and safety of electronic nicotine delivery systems (ENDS) (through March 1, 2015) and a search...”

10 “... to the effectiveness and safety of electronic nicotine delivery systems (ENDS) (through March 1, 2015) and a search...”

11 “... criteria. DATA ANALYSIS: One investigator abstracted data into an evidence table and a second investigator...”

12 “... criteria. DATA ANALYSIS: One investigator abstracted data into an evidence table and a second investigator...”

13 “... to 1.03]). Absolute risk reductions in major CVD events in the trials ranged from 0.08 to 2.5 percent...”

14 “...Two trials reported conflicting results on total or fatal hemorrhagic CVA risk with wide confidence...”

15 “...Two trials reported conflicting results on total or fatal hemorrhagic CVA risk with wide confidence...”

16 “... across a range of patient outcomes. One of the two trials (n=114) evaluating the same exercise-focused...”

17 “...One fair-quality study examined a staged approach whereby the screening test was considered...”

18 “...One fair-quality study examined a staged approach whereby the screening test was considered...”

19 “.... One investigator abstracted data into an evidence table and a second investigator checked these data....”

20 “.... One investigator abstracted data into an evidence table and a second investigator checked these data....”