1 Subjects: “...Research Design...”

2 “..., study design features, outcomes reported, intervention and outcome descriptions, and results data...”

3 “..., study design features, outcomes reported, intervention and outcome descriptions, and results data...”

4 “... with disease: one where the two research designs generally agree and one where they disagree. STUDY DESIGN...”

5 “... with disease: one where the two research designs generally agree and one where they disagree. STUDY DESIGN...”

6 “... mortality. DESIGN: We conducted a systematic review with random effects meta-analysis and mixed effects dose...”

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8 “... intervention given to all subjects included in the study design. The utility and limitations of single group...”

9 “... (P for trend < 0.001), prospective study design (P for trend < 0.001), or consecutive patient...”

10 “... (P for trend < 0.001), prospective study design (P for trend < 0.001), or consecutive patient...”

11 “... criteria. DATA EXTRACTION: A standardized protocol was used to extract details on design, diagnoses...”

12 “... criteria. DATA EXTRACTION: A standardized protocol was used to extract details on design, diagnoses...”

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20 “...DESIGN: Randomized clinical trials (RCTs) of secondary prevention programs in patients with CAD...”