1 “... to usual care. We identified 125 QOL or symptom measure tools used in 165 studies. Ten tools were designed...”

2 “...The term "targeted therapies" refers to antineoplastic treatments designed not to kill cells...”

3 “...The term "targeted therapies" refers to antineoplastic treatments designed not to kill cells...”

4 “...) was designed to respond to three specific questions posed by the Centers for Medicare and Medicaid Services...”

5 “...) was designed to respond to three specific questions posed by the Centers for Medicare and Medicaid Services...”

6 “... in a standardized manner. Our recommendations about stronger approaches to designing and conducting TRD...”

7 “... in a standardized manner. Our recommendations about stronger approaches to designing and conducting TRD...”

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12 “... of comparator groups, variable quality in study design, and limited reporting of outcomes. CONCLUSIONS: We were...”

13 “... of comparator groups, variable quality in study design, and limited reporting of outcomes. CONCLUSIONS: We were...”

14 “..., in conjunction with other data, to deliberate on the trial designs that will be needed to support the development...”

15 “...Only 15 studies had a design and/or analytical approach that allowed inferences for causal...”

16 “...Only 15 studies had a design and/or analytical approach that allowed inferences for causal...”

17 “..., in conjunction with other data, to deliberate on the trial designs that will be needed to support the development...”

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20 “... or computer/robotic assisted); the design of the replacement prosthesis (metal-on-plastic, metal-on-metal...”