1 “...Methods research report...”

2 Subjects: “...Bias...”

3 “...Technology assessment report...”

4 “...Technology assessment report...”

5 “... included systematic reviews reporting on anticoagulation benefits or harms and observational studies...”

6 “...). REVIEW METHODS: Two investigators independently selected, extracted data from, and rated risk of bias...”

7 “...). REVIEW METHODS: Two investigators independently selected, extracted data from, and rated risk of bias...”

8 “... above. Pairs of reviewers independently selected, extracted data from, and rated the risk of bias...”

9 “... data from, and rated risk of bias of relevant studies. We conducted meta-analyses or network meta...”

10 “... data from, and rated risk of bias of relevant studies. We conducted meta-analyses or network meta...”

11 “... was similar, and (4) studies were double-blinded randomized controlled trials of low or medium risk of bias...”

12 “... above. Pairs of reviewers independently selected, extracted data from, and rated the risk of bias...”

13

14 “... was similar, and (4) studies were double-blinded randomized controlled trials of low or medium risk of bias...”

15