1

2 Subjects: “...Chronic Pain / drug therapy...”

3 Subjects: “...Fatigue Syndrome, Chronic / therapy...”

4 Subjects: “...Chronic Pain / therapy...”

5

6

7 “... intervention. Effect sizes were generally small for function and pain.CHRONIC LOW BACK PAIN: Psychological...”

8 Subjects: “...Chronic Pain / therapy...”

9 Subjects: “...Chronic Pain / drug therapy...”

10

11

12

13

14 Subjects: “...Chronic Pain / drug therapy...”

15 “... or in other subgroups. CONCLUSIONS: Evidence on long-term opioid therapy for chronic pain is very limited...”

16 Subjects: “...Chronic Pain / therapy...”

17

18

19 “... compounds to treat chronic pain. DATA SOURCES: Ovid(r) MEDLINE(r), PsycINFO(r), Embase(r), the Cochrane...”

20 Subjects: “...Chronic Disease...”